New Medicines Require a New Way of Thinking

Our Mission

Senti Bio was founded to create a new generation of smarter medicines that outsmart complex diseases using novel and unprecedented approaches.

Founded on Smart Science

Senti Bio is a clinical-stage company that has built a synthetic biology platform that enables us to program next-generation cell and gene therapies with Gene Circuits. These Gene Circuits, created from novel and proprietary combinations of DNA sequences, are designed to precisely kill cancer cells, spare healthy cells, increase specificity to target cells and control the expression of drugs even after administration. We are applying our Gene Circuit technologies to develop a pipeline of product candidates that use off-the-shelf chimeric antigen receptor natural killer (CAR-NK) cells.

Driven by Strong Leadership

Senti Bio is led by seasoned professionals with a passion for advancing life-changing therapies.

Chief Executive Officer and Co-founder, Dr. Tim Lu, is a pioneer in synthetic biology and has co-founded multiple therapeutics platform companies including Synlogic, Tango Therapeutics, Eligo Bioscience, BiomX and Engine Biosciences. Interim Chief Financial Officer and Treasurer, Yvonne Li, is a dynamic leader who inspires and empowers her team to achieve their full potential, cultivating a culture of trust and accountability that results in high-performing teams. Head of Research & Development and Chief Medical Officer, Dr. Kanya Rajangam, is an experienced biotechnology executive with an extensive track record of successfully developing products across multiple modalities including allogeneic cell therapies.

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Watch How Senti is Creating Smarter Medicines

The Senti Bio’s Development Approach

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Our Innovation Values

Our goal is to become an industry leader in the cell and gene therapy landscape. We are pursuing this goal by advancing our unique approach to developing intelligent Gene Circuits for use in next-generation cell and gene therapies with a focus on oncological diseases.

Our commitment to advancing medicine is based on these core values.

Be Bold

We must never become complacent or afraid to be different.

Better Together

Building and nurturing an inclusive culture that encourages collaboration.

Build to Last

We are here to try to make a lasting impact for countless lives for generations to come.