New medicines require a new way of thinking.

Our mission

Senti Bio was founded to create a new generation of smarter medicines that outmaneuver complex diseases using novel and unprecedented approaches.

Founded on smart science

Senti Bio has built a synthetic biology platform that enables it to program next-generation cell and gene therapies with what we refer to as “gene circuits.” These gene circuits, which are created from novel and proprietary combinations of DNA sequences, reprogram cells with biological logic to sense inputs, compute decisions and respond to their cellular environments.

Senti is built on the shoulders of those who have come before. We believe in the power of knowledge and data to overcome any barriers to success.
Driven by strong leadership

Senti Bio is led by seasoned professionals with a passion for building life-changing therapies. Chief Executive Officer and Co-founder, Dr. Tim Lu, is a pioneer in synthetic biology and has co-founded multiple therapeutics platform companies including Synlogic, Tango Therapeutics, Eligo Bioscience, BiomX and Engine Biosciences. Chief Financial Officer and Head of Corporate Development, Dr. Deborah Knobelman, is a proven life science executive with broad financial experience spanning senior leadership roles in biopharma companies and Wall Street. Head of Research & Development and Chief Medical Officer, Dr. Kanya Rajangam, is an experienced biotechnology executive with an extensive track record of successfully developing products across multiple modalities including allogeneic cell therapies.

The Senti Bio development approach

Our innovation values

Our goal is to become an industry leader in the cell and gene therapy landscape. We are pursuing this goal by advancing our unique approach to developing and manufacturing intelligent gene circuits for use in next-generation cell and gene therapies across therapeutic areas and modalities.

Our commitment to advancing medicine is based on these core values.
Be Bold

We must never become complacent or afraid to be different.

Better Together

All our voices must be heard so we can outsmart these complex diseases.

Build to Last

We are here to try and make a lasting impact for countless lives and for generations to come.