New Medicines Require a New Way of Thinking
Our Mission
Senti Bio was founded to create a new generation of smarter medicines that outsmart complex diseases using novel and unprecedented approaches.
Founded on Smart Science
Senti Bio is a clinical-stage company developing a new generation of cell and gene therapies for patients living with difficult to treat and incurable diseases. To achieve this, we are leveraging our synthetic biology platform to engineer Gene Circuits into new medicines with enhanced precision and control. These Gene Circuits are designed to precisely kill cancer cells, spare healthy cells, increase specificity to target tissues and/or to be controllable even after administration. Our wholly-owned pipeline is comprised of cell therapies engineered with Gene Circuits to target challenging liquid and solid tumor indications, and our Gene Circuits have been shown to work clinically and preclinically, and to work in both NK and T cells which allows us to select the right cell type for each indication. We have demonstrated the potential depth and breadth of Gene Circuits in other modalities and diseases outside of oncology preclinically, and continue to advance these capabilities through partnerships and alone.
Driven by Strong Leadership
Senti Bio is led by seasoned professionals with a passion for advancing life-changing therapies.
Co-Founder and Chief Executive Officer, Dr. Tim Lu, is a pioneer in synthetic biology and has co-founded multiple therapeutics platform companies including Tango Therapeutics, Eligo Bioscience, and Engine Biosciences. Chief Financial Officer, Jay Cross, is a proven financial leader with extensive experience as a healthcare investment banker on Wall Street. President, Head of Research & Development and Chief Medical Officer, Dr. Kanya Rajangam, is an experienced biotechnology executive with an extensive track record of successfully developing multiple globally approved products across multiple modalities including allogeneic cell therapies.
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Watch How Senti is Creating Smarter Medicines
Senti Bio’s Development Approach
Our Innovation Values
Our goal is to become an industry leader in developing novel therapies for hard to treat diseases. We are pursuing this goal by advancing our unique approach to developing intelligent Gene Circuits for use in next-generation cell and gene therapies with a focus on oncological diseases.
Our commitment to advancing medicine is based on these core values.
Be Bold
We must never become complacent or afraid to be different.
Better Together
Building and nurturing an inclusive culture that encourages collaboration.
Build to Last
We are here to try to make a lasting impact on countless lives for generations to come.