New medicines require a new way of thinking.

Our mission

To create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable.

Founded on smart science

Senti Bio has built a synthetic biology platform that enables it to program next-generation cell and gene therapies with “gene circuits.” These gene circuits, which are created from novel and proprietary combinations of DNA sequences, reprogram cells with biological logic to sense inputs, compute decisions and respond to their cellular environments.

Senti is built on the shoulders of those who have come before. We believe in the power of knowledge and data to overcome any barriers to success.
Driven by strong leadership

CEO and co-founder, Tim Lu, brings his expertise in computer programming, electrical engineering and microbiology to Senti. Tim started the company in 2016 with former MIT classmate Philip Lee, who received his PhD from UC Berkeley’s Graduate Program in Bioengineering and is the former Director of New Business at Merck KGaA. Senti Bio’s team is comprised of industry-leading experts, including scientists, engineers, advisors and company-builders—all with a deep knowledge of synthetic biology, gene circuits and cell and gene therapy.

The Senti Bio development approach

Senti Bio thinks broadly about how it can improve health outcomes for many people. In doing so, the entire organization remains focused on iterative improvement of gene circuit technology. Senti Bio continues to assemble an amazing interdisciplinary team to design, test and learn together every day.

Our innovation values

Our goal is to become an industry leader in the cell and gene therapy landscape. We are pursuing this goal by advancing our gene circuit platform to discover, develop, manufacture and globally commercialize new classes of cell and gene therapies across therapeutic areas and modalities.

Our commitment to advancing medicine is based on these core values.
Be Bold

We must never become complacent or afraid to be different.

Better Together

All our voices must be heard so we can outsmart these complex diseases.

Build to Last

We are here to try and make a lasting impact for countless lives and for generations to come.

Our headquarters

Located at the center of science and technology in South San Francisco, we are surrounded by like-minded innovators and biotech leaders.

Senti Bio
2 Corporate Drive, First Floor
South San Francisco, CA 94080