Gene Circuit Technology Platform
Gene Circuits: Deployable into any Cell or Vector
Gene circuits can be deployed into a range of modalities for next-generation cell and gene therapies. We believe that gene circuit therapies may address unmet needs across multiple therapeutic areas.
Building the Future of Cell Therapies for Cancer Patients
We are developing product candidates to overcome key challenges for cell therapies in cancer, for both liquid and solid tumors. We are working on advanced targeting strategies to enable our cell therapies to eliminate cancerous cells while sparing healthy cells. We are also developing controlled cell therapies that feature tunable expression of potent payloads in order to drive optimal efficacy within the therapeutic window. These combinations of powerful immune effector payloads help to overcome tumor immune evasion and to prolong the persistence of the cellular therapies.
Challenges to Existing Cell Therapy Paradigm
Tumor Antigen Heterogeneity
Limited Therapeutic Window
Tumor Immune Evasion
Senti Bio's Gene Circuit-Enabled Features